GLP1 Menopause Journal

I am Melissa — a 62-year-old woman who lost 100 pounds, gained 50 back during menopause, and figured out GLP-1 the hard way. This is where I write about what actually works. No filters. No shortcuts. Just real talk for women after 45.

HRT and Zepbound: What the Research Actually Says

HRT and Zepbound: What the Research Actually Says

HRT and Zepbound: What the Research Actually SaysMelissa
Published on: 06/04/2026

A Mayo Clinic study found women on HRT lost 35% more weight on tirzepatide. I was already on both. Here's what that means.

Menopause and GLP-1
GLP-1 Muscle Loss in Menopause: I Lost the Wrong Weight

GLP-1 Muscle Loss in Menopause: I Lost the Wrong Weight

GLP-1 Muscle Loss in Menopause: I Lost the Wrong WeightMelissa
Published on: 05/28/2026

I lost 47 pounds on Zepbound. But not all of it was fat. Here is what GLP-1 muscle loss looks like in menopause, and what I do about it now.

Menopause and GLP-1
Ozempic Personality: Is GLP-1 Changing Who You Are?

Ozempic Personality: Is GLP-1 Changing Who You Are?

Ozempic Personality: Is GLP-1 Changing Who You Are?Melissa
Published on: 05/21/2026

I thought I was finally becoming a calm, evolved person. Then I realized it might be the medication. Here's what Ozempic personality actually is.

Menopause and GLP-1
I'm 62 on GLP-1 and in menopause.  Here's What I Wish I'd Known at 57.

I'm 62 on GLP-1 and in menopause. Here's What I Wish I'd Known at 57.

I'm 62 on GLP-1 and in menopause.  Here's What I Wish I'd Known at 57.Melissa
Published on: 05/07/2026

I lost 100 pounds, held it for years, then menopause pushed me 40 pounds from my goal. I started Zepbound at 57. Here are the 5 mistakes nobody warned me about.

Personal Story

Everything on this blog is based on my own personal experience as a woman navigating GLP-1 and menopause. I am not a doctor, dietitian, or medical professional. Nothing here should be taken as medical advice. Always consult your healthcare provider before making changes to your diet, exercise, or medication routine.